Association of Class I Human Leukocyte Antigen in Iraqi Patients with Hodgkin’s Lymphoma
Article Sidebar
-
Class I human leukocyte antigen, Hodgkin’s lymphoma
Abstract
Objective:-
To assess the correlation between human leukocytes antigen class I in Iraqi patients with Hodgkin’s lymphoma.
Subject and Methods:-
A study was conducted in period between the June 2003 and November, 2004. Study groups included 80 newly diagnosed Hodgkin’s lymphoma patients and two control groups, patient controls which include 50 newly diagnosed by Non Hodgkin’s lymphoma and 50 healthy controls. Antibody-Mediated complement dependent cytotoxicity assay was done by treating sample of patient's lymphocytes with a panel of anti- human leukocyte antigen antisera and complement.
Results:-
The frequency expression of human leukocyte antigen- A1, A28, B5, B51 and Cw7 was significantly greater in Hodgkin’s lymphoma patients compared to healthy control group with (p <0.001) for human leukocyte antigen- A1, A28 and Cw7 and (p <0.01) for B5 and B51.
Conclusion:-
Human leukocyte antigen- A1, A28, B5, B51 and Cw7 are more related with Hodgkin’s lymphoma in Iraqi population that reflects allelic association to Hodgkin’s lymphoma.
Full text article
Authors
Copyright (c) 2013 Ruqaya M. Al-Barzinji
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License [CC BY-NC-SA 4.0] that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work, with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online.